ea0014oc7.2 | Reproductive endocrinology I | ECE2007
Cariboni Anna
, Rakic Sonja
, Hickok Jason
, Andrews William
, Tischkau Shelley
, Maggi Roberto
, Parnavelas John
Reproduction in mammals is centrally regulated by neuroendocrine neurons scattered in the hypothalamus and secreting the decapeptide GnRH (gonadotropin releasing hormone). During development, GnRH-secreting neurons originate in the olfactory placode at least in rodents and migrate along olfactory nerves (the vomeronasal and the terminalis) to gain access to the forebrain and reach their final destinations in the hypothalamus. Defects in the migration of these neu...